Thoracic.org - Women who are stressed during pregnancy may pass some of that stress-distress condition to their babies in the form of increased sensitivity to allergen exposure and possibly future asthma risk, according to researchers from Harvard Medical School who are presenting their findings at the American Thoracic Society’s 2008 International Conference in Toronto on Sunday, May 18, 2008. thoracic.org -妇女谁是强调，在怀孕期间可能通过一些应力-遇险条件对她们的婴儿在的形式增加的敏感性，过敏原接触以及可能未来哮喘的风险，据研究人员从哈佛医学院的谁是介绍他们的研究结果在美国胸腔学会的2008年国际会议在加拿大多伦多星期日， 2008年5月18日。

“While predisposition to asthma may be, in part, set at birth, the factors that may determine this are not strictly genetic. “而易感性哮喘的可能，这在部分设置在出生时，的因素可确定这是由于没有严格的遗传。 Certain substances in the environment that cause allergies, such as dust mites, can increase a child’s chance of developing asthma and the effects may begin before birth,” said Rosalind J. Wright, MD, MPH, assistant professor of medicine at Brigham & Women’s Hospital and Harvard Medical School.某些物质在环境中导致过敏，如尘螨，可以增加儿童的发展的机会和哮喘的影响，可能在出生前就开始，说： “罗莎琳德赖特j. ，海事处，英里每小时，助理医学教授布里格姆＆妇女医院和哈佛医学院。

Mother’s stress during pregnancy can also influence the babies developing immune system.母亲的强调，在怀孕期间也可以影响婴儿免疫系统的发展。 While animal studies suggest that the combination of stress and allergen exposure during pregnancy may magnify the effects on the immune system, this is the first human study to examine this directly.虽然动物研究表明，相结合的应力和过敏原暴露在怀孕期间可能放大的影响，对免疫系统，这是人类第一次进行研究，探讨，这直接。 The researchers analyzed levels of maternal stress and mother’s exposure to dust mite allergen in their homes while pregnant with respect to cord blood IgE expression - a marker of the child’s immune response at birth - in 387 infants enrolled in the Asthma Coalition on Community, Environment, and Social Stress (ACCESS) project in Boston.研究人员分析了各级产妇应力和母亲的接触到尘螨变应原在自己的家园而怀孕方面的脐带血IgE的表达-一个标记该儿童的免疫反应在出生时-在3 8 7婴幼儿就读于哮喘联盟就社会，环境和社会压力（存取）项目在波士顿。

They found increased levels of IgE expression in cord blood among infants whose mothers experienced higher level stress even when exposed to relatively low levels of dust mite during pregnancy.他们发现，增加各级IgE的表达在脐血婴儿的母亲经历了更高层次强调，即使暴露在相对较低的水平，尘螨在怀孕期间。 This indicates that mother’s stress during pregnancy magnified the effect of dust exposure on the child’s immune system such that the child’s immune response at birth may be altered even with lower levels of dust exposure in the home.这表明，母亲的压力在怀孕期间的放大效应粉尘暴露对儿童的免疫系统，例如该儿童的免疫反应在出生时可能会改变，甚至水平较低的粉尘暴露于家中。 The results held true regardless of the mother’s race, class, education or smoking history.结果举行的真实，不论母亲的种族，阶级，教育或吸烟史。

“This research adds to a growing body of evidence that links maternal stress such as that precipitated by financial problems or relationship issues, to changes in children’s developing immune systems, even during pregnancy,” said Dr. Wright. “这项研究增加了越来越多的证据表明，链接产妇强调，例如像沉淀的财政问题或关系的问题，改变在儿童发展的免疫系统，甚至在怀孕期间，医生说： ”赖特。 “This further supports the notion that stress can be thought of as a social pollutant that, when ‘breathed’ into the body, may influence the body’s immune response similar to the effects of physical pollutants like allergens, thus adding to their effects.” “这进一步支持的概念，强调可以被认为是作为一种社会的污染物，当'吹'到人体，可能会影响人体的免疫反应，类似的影响，物理污染物一样，过敏原，从而增加了他们的影响。 “

While these findings are important, Dr. Wright noted that only with continued follow-up of these children will they know if these effects will result in increased asthma risk.虽然这些结果是非常重要的，赖特博士指出，只有不断的后续行动，这些儿童将他们知道如果这些影响将导致在增加哮喘的风险。 Moreover, it will be important to replicate these findings in larger populations to give a clearer picture of the relationship between prenatal maternal stress, allergen exposure and subsequent childhood asthma development.此外，它将会是很重要的复制这些研究结果在较大的人口提供一个清晰的图片之间的关系，产前产妇强调，过敏原的暴露和随后的儿童哮喘的发展。

“It is notable that these findings were obtained in a US urban population, which may be more likely to be simultaneously exposed to multiple factors, including stress and indoor allergens. “这是值得注意的是，这些调查结果，获得了在美国的城市人口，这可能是更可能的同时，暴露于多种因素，包括压力和室内过敏原。 More studies like this may help explain why asthma occurs more frequently in these high-risk groups,” said Junenette Peters, Sc.D., postdoctoral research fellow who presented these results.更多的研究一样，这可能有助于解释为什么哮喘的发生更频繁地在这些高危险群，说： “ junenette彼得斯， sc.d. ，博士后研究员谁介绍这些结果。

In the meantime, the findings suggest that when such exposures - prenatal stress, allergen exposure - occur together, there is a magnified increase in risk, which supports the assessment of maternal psychological well-being along with other environmental factors as part of a prenatal health program.在此同时，调查结果显示，当这种风险-产前应激，过敏原接触-发生一起，有一个放大了的增加的风险，它支持的评估产妇的心理福祉，一直与其他环境因素的一个组成部分，产前保健程序。

Reference: “Psychological Stress Modifies the Influence of Prenatal Allergen Exposure on Cord Blood IgE: The Boston ACCESS Project” (Session A92; Abstract #4746).参考： “心理应激修改的影响，产前过敏原暴露于脐带血IgE的：波士顿Access项目” （会议a92 ;摘要编号4746 ） 。