Low vitamin D level worsens arthritis in knees低维生素d水平恶化关节炎膝盖
Published November 8th, 2007 in 出版2007年11月8日在 Health News 健康新闻 , , Nutrition 营养 , , Vitamin D 维生素d , , Medical News 医疗新闻 , , Medicine 医药 , , Health 健康 , , Health and Wellness 保健和健康 , , Popular 流行 , , General Interest 一般利益Newswise — Low vitamin D levels may cause greater knee pain and difficulty walking in patients with knee osteoarthritis, according to research presented this week at the American College of Rheumatology Annual Scientific Meeting in Boston, MA. newswise -低维生素d水平可能造成更大的膝关节疼痛及步行困难患者的膝关节骨性关节炎,据考证介绍了本星期在美国大学的风湿病学年度科学会议即将召开,在波士顿,麻。
Knee osteoarthritis is caused by cartilage breakdown in the knee joint.膝骨关节炎是由于关节软骨破裂,膝关节。 Factors that increase the risk of knee osteoarthritis include being overweight, age, injury or stress to the joints, and family history can increase the risk of knee osteoarthritis.因素增加人们患膝骨关节炎包括超重,年龄,受伤或胁迫,以关节和家族史,可以增加人们患膝骨关节炎。
Recent studies have shown that vitamin D influences both musculoskeletal and neuromuscular function.最近的研究显示,维生素d的影响,无论肌肉骨骼和神经肌肉功能。 Taking a closer look at this, in a two-year trial of vitamin D supplements on knee osteoarthritis progression, researchers tested whether vitamin D deficiency at study entry is associated with pain and physical function in OA patients.同时仔细看看这一点,在一项为期两年的试验,维生素d补充剂对膝骨关节炎的进展,研究人员检测是否维生素d缺乏在研究相关疼痛及身体功能,在办公自动化的病人。 Researchers studied 65 women and 35 men in their sixties who showed signs of having knee OA by measuring blood levels of vitamin D, their baseline knee pain, the time needed for arising several times from a chair, and the time needed to walk 20 meters.研究人员调查了65名妇女和35名男子六十人的迹象后,膝骨关节炎通过测量血液中维生素d水平,其基准膝部疼痛,需要的时间,所带来的几倍,从在椅子上,和所需要的时间步行20米。
Of the 100 participants, 47 percent were vitamin D deficient, with vitamin D levels below 30 ng/ml.的100人参加,有47 %的人,维生素d缺乏,维生素d水平低于30 ng / ml的。 This deficiency contributed to increased pain and difficulty walking among the participants.这个缺憾有助于增加了痛苦和难以行走是与会者之一。 However, the deficiency did not affect time need to stand and sit repeatedly.然而,缺失并不影响时间需要站立,仰卧起坐反复。
Vitamin D promotes the absorption of calcium and phosphorus needed for bone mineralization, growth and repair.维生素d促进吸收钙,磷所需要的骨骼矿化,生长和修复。 Sources of vitamin D are available to a lesser extent from dietary sources typically found in fortified margarine, oily fish, liver, fortified breakfast cereals and dairy products.来源维生素d ,可在较小的程度上,从饮食来源通常生活在森严的人造黄油,油性鱼类,肝脏,森严的早餐谷物和乳制品。 Sun exposure helps vitamin D to become active.暴露在阳光下,有助于维生素d成为活跃。
Absorption of vitamin D from food and conversion of it to the active form is less efficient in elderly persons.吸收的维生素d ,从食品和成果转化的,它以积极的形式,是效率较低的中老年人。 For this reason, vitamin D supplements of 400-800 IU and calcium doses of 1,200 to 1,500 mg a day are recommended to prevent osteoporosis.正因为如此,维生素d补充400-800国际单位,钙剂量的1200年至1500年毫克,每天都建议,以防止骨质疏松症。 The results of this study suggest that vitamin D supplements may also help in arthritis treatment.这项研究的结果表明,维生素d的补充也可帮助在关节炎治疗。
“These preliminary results suggest that, among people with knee osteoarthritis, having a low vitamin D level is associated with more knee pain and greater functional limitation,” said Tim McAlindon, MD, MPH; associate professor of medicine, division of rheumatology, Tufts New England Medical Center; and an investigator in the study. "这些初步结果表明,人与人之间膝骨性关节炎,具有低维生素d水平,是与更多的膝盖疼痛和更大的功能性缺陷,说: "添mcalindon ,海事处,英里每小时;副教授医药司,风湿病,塔夫茨新英格兰医疗中心,并在调查研究的。 “Future results from this ongoing randomized, double-blinded, placebo-controlled clinical trial of vitamin D will help determine whether vitamin D is an effective disease-modifying intervention for knee osteoarthritis.” "未来的结果,从这种持续的随机,双盲,安慰剂对照临床试验的维生素d ,将有助决定是否维生素d是一个有效的疾病修饰介入治疗膝骨关节炎" 。













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