600,000 cases a year of breast and colon / rectal cancer could be prevented each year by adequate intake of vitamin D3. 600000个案每年乳腺癌和结肠/直肠癌可以预防每年摄入足够的维生素d3 .

UCSD - A new study looking at the relationship between vitamin D serum levels and the risk of colon and breast cancer across the globe has estimated the number of cases of cancer that could be prevented each year if vitamin D3 levels met the target proposed by researchers.加州大学一项新研究中的关系,维生素d血清和罹患结肠癌和乳腺癌全球各地估计有多少宗癌症是可以预防的,每年如果维生素d3水平达到目标所提出的研究员.

Cedric F. Garland, Dr.P.H., cancer prevention specialist at the Moores Cancer Center at the University of California, San Diego (UCSD) and colleagues estimate that 250,000 cases of colorectal cancer and 350,000 cases of breast cancer could be prevented worldwide by increasing intake of vitamin D3, particularly in countries north of the equator.  Vitamin D3 is available through diet, supplements and exposure of the skin to sunlight.塞德里克f.嘉云, dr.p.h. ,预防癌症专科在著作权癌症中心的加利福尼亚大学圣迭戈分校,圣迭戈(分校)和他的同事估计, 25例大肠癌和35例乳腺癌可以避免全世界越来越多摄取维生素d3 ,尤其是在国家赤道以北.维生素d3 ,可通过饮食,补充剂和暴露皮肤的阳光.

“For the first time, we are saying that 600,000 cases of breast and colorectal cancer could be prevented each year worldwide, including nearly 150,000 in the United States alone,” said study co-author Garland.   The paper, which looks at the dose-response relationship between vitamin D and cancer, will be published in the August 2007 edition of the journal Nutrition Reviews . "这是第一次,我们说了60例乳腺癌和大肠癌是可以预防每年在世界范围内,其中包括近15万,仅在美国,说: "该研究的合著花环.文件,它看上去在剂量-反应关系,维生素d和癌症,将刊登在2007年8月杂志营养评语 .

The study combined data from surveys of serum vitamin D levels during winter from 15 countries.  It is the first such study to look at satellite measurements of sunshine and cloud cover in countries where actual blood serum levels of vitamin D3 had also been determined.  The data were then applied to 177 countries to estimate the average serum level of a vitamin D metabolite of people living there.该研究结合调查数据来自血清维生素d水平冬季期间,来自15个国家.这是首个研究看看卫星测量阳光和云层的国家实际血液中的血清维生素d3也已确定.数据当时适用于177个国家,估计平均血清服用维生素d代谢物的人在那里生活.

The data revealed an inverse association of serum vitamin D with risk of colorectal and breast cancer.  The protective effect began at levels ranging from 24 to 32 nanograms per milliliter of 25-hydroxy-vitamin D concentration in the serum.  The 25-hydroxyvitamin D level is the main indicator of vitamin D status.  The late winter average 25-hydroxyvitamin D in the US is about 15-18 ng/ml.数据显示,逆协会血清维生素d与患结肠和乳腺癌.保护作用始于水平24至32微克每毫升25 -羟基维生素d浓度血清. 25羟维生素d水平这是我们主要指标维生素d的地位.已故冬季平均25 -羟四,在美国约为15-18伍/毫升. The researchers maintain that increasing vitamin D levels in populations, particularly those in northern climates, has the potential to both prevent and possibly serve as an adjunct to existing treatments for cancer.研究者认为增加维生素d水平的人群中,尤其是在北方气候条件,有潜力,以防止可能充当辅助现有的癌症疗法.

The work builds on previous studies by Garland and colleagues ( Journal of Steroid Biochemistry and Molecular , February 2007) which found that raising the serum 25(OH)D levels to 55 ng/mL was optimal for cancer prevention.  This is the first study to recommend optimal vitamin D serum levels which, Garland said, are high enough to provide the needed benefit but which have been found by other scientists to be low enough to avoid health risks.工作是建立在以往的研究中,由嘉云和同事( 杂志类固醇生物化学和分子 , 2007年2月) ,该组织发现,提高血清25 ( oh ) d水平至55 ng / ml的是最适用于预防癌症.这是首次研究推荐最佳维生素d血清,其中加兰说,够高,以提供所需的好处,但都被其他科学家够低,以避免健康风险.

“This could be best achieved with a combination of diet, supplements and short intervals – 10 or 15 minutes a day – in the sun,” said Garland.  It could be less for very fair-skinned individuals. "这可以取得最佳相结合的饮食,补充剂和短间隔10或15分钟,每天在阳光下时,说: "花环.它可以减少非常皮肤个人. He went on to say that “the appropriate dose of vitamin D in order to reach this level, could be very little in a lifeguard in Southern California… or quite a lot for someone in Northern Europe who tends to remain indoors most of the year.”他接着说: "适当剂量的维生素d ,以达到这个水平,可很少救生员在南加州… …还是不少,有人在北欧国家的人倾向于留在室内一年的大部分时间. "

The serum level recommended by the study would correspond to intake of 2000 International Units per day of vitamin D3 for a meaningful reduction in colorectal cancer.血清研究报告的建议,将相当于摄入2000国际单位,每天摄入维生素d3有意义的减少肠癌. The researchers recommend 2000 IU/day, plus, when weather allows, a few minutes in the sun with at least 40% of the skin exposed, for a meaningful reduction in breast cancer incidence, unless the individual has a history of skin cancer or a photosensitivity disorder.研究者建议, 2000年福耀/日,加,当天气允许的话,几分钟太阳,至少有40 %的皮肤暴露出来,为切实减少乳腺癌的发病率,除非个人有史皮肤癌或光敏性疾病.

Garland also recommends moderate sun exposure and use of clothing and a hat when in the sun longer than 15 minutes.嘉云还建议适度晒太阳,并用衣服和帽子时,在太阳下超过15分钟.

This paper used worldwide data only recently available through a new tool called GLOBOCAN, developed by the World Health Organization’s International Agency for Research on Cancer.本文所采用的数据,全世界只有最近获得通过的一个新工具叫globocan开发世界卫生组织的国际癌症研究机构. GLOBOCAN is a database of cancer incidence, mortality and prevalence for 177 countries.  Previous studies from this core group have shown an association between higher levels of vitamin D3 or markers of vitamin D status and lower risk of cancers of the breast, colon, ovary and kidney.  The researchers underscore their call for prompt public health action to increase intake of vitamin D3 as an inexpensive tool for prevention of diseases that claim nearly one million lives each year world wide. globocan是一个数据库的癌症发病率,死亡率和患病率,为177个国家.以往的研究,从这个核心小组均已表明关联程度较高的维生素d3或标记维生素d地位,并降低风险,乳癌,结肠癌,卵巢和肾脏.研究者强调,他们要求及时公共卫生行动,以增加摄入维生素d3作为一种廉价的工具,为预防疾病,索赔近100万人的生命,每年世界各地.

“The message is, depending on where you live, you may need to consider taking in considerably higher levels of vitamin D3 than those currently recommended,” said Garland. "的讯息是,这取决于你住的,你可能需要考虑在相当高的水平维生素d3比目前推荐的,说: "花环. “I’d recommend discussing vitamin D needs with a health care professional, who may order and interpret a simple blood test for a vitamin D metabolite [25(OH)D], and provide a dosage recommendation that’s appropriate for the individual’s needs” of vitamin D3. "我建议在讨论维生素d需要与保健专业人士,为了诠释一个简单的血液测试服用维生素d代谢[ 25 (噢)丁] ,并提供用药建议的适合个别'美国需要"维生素d3 .