Proven treatments for aging skin include niacin, N-acetyl glucosamine, retinoids, and UVA blockers.

Blackwell Publishing – Cosmeceuticals, beauty aids that reportedly work like prescription drugs, are providing new ways to treat aging skin. A study recently published in the Journal of Cosmetic Dermatology explores a variety of new ingredients in cosmeceuticals that provide a visibly noticeable improvement in maturing skin.

The most dramatic and apparent signs of aging include the lack of skin surface regularity, formation of wrinkles, and increased presence of abnormal pigmentation. Zoe Diana Draelos, MD, of Dermatology Consulting Services, High Point, North Carolina, assessed the ingredient efficacy in a variety of cosmeceuticals on each of these areas of aging skin.

Draelos found that skin surface irregularity can be improved through the topical application of niacin (niacinamide), while the appearance of fine lines can be diminished through the application of moisturizers containing engineered peptides and over-the-counter retinoids, such as retinyl propionate. Skin pigmentation can become more regular with the topical use of N-A-G (N-acetyl glucosamine) and photoprotective ingredients (that block ultraviolet A). Furthermore, combining cosmeceutical ingredients in a moisturizing agent can magnify benefits and improve skin appearance.

“Evidence-based cosmeceutical ingredients can provide anti-aging benefits,” Draelos concludes. “This new generation of cosmeceuticals can provide valuable skin benefits” (Journal of Cosmetic Dermatology, Volume 6 Issue s1, pgs 2-6, December 2007).


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